ReconEval#

Benchmark for gene-expression reconstruction from single-cell latent representations. The package contains:

  • a metrics API that scores a (true, reconstructed) anndata.AnnData pair (statistical, biological, perturbational);

  • four tutorial notebooks covering the three benchmark settings;

  • training and eval pipelines under experiments/ with Hydra configs and sbatch wrappers;

  • analysis notebooks under analysis/ that reproduce the paper figures from cached metric CSVs.

Install

pip install -e . for the metrics API; conda env for the full benchmark.

Installation
Tutorials

Metrics, end-to-end, foundation-model and latent-shift reconstruction notebooks.

Tutorials
API reference

Public functions and classes in sc_reconstruction.

API reference
Experiments

Training drivers, eval scripts, sbatch wrappers and Hydra configs per task.

Experiments
Reproducibility

Analysis notebooks that reproduce the paper figures.

Reproducibility
Manuscript

Preprint: TBD.

https://example.org/preprint